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Thermo Fisher ScientificBiotechnology

mRNA Analytical Development Scientist

Italy , Monza
Full-time

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting, Office

Job Description

About the role

Help develop the analytical methods behind next-generation mRNA products. In this hands-on laboratory role, you’ll use your HPLC expertise to generate high-quality data, solve analytical challenges and support method transfer to QC and GMP laboratories.

You’ll join a fast-paced team of scientists with a strong scientific background, working hands-on to develop and characterize mRNA products.


What you’ll do

  • Perform laboratory analyses to support mRNA product development and characterization.
  • Use HPLC to generate reliable data and investigate analytical challenges.
  • Contribute to method transfer to QC and GMP laboratories.
  • Analyze and communicate results to project teams.
  • Prepare clear, accurate and traceable technical documentation.
  • Collaborate with colleagues across analytical development, process development, QC and manufacturing.

What you’ll bring

  • A PhD in analytical chemistry, biochemistry, biotechnology, pharmaceutical sciences or a related discipline, or relevant hands-on experience in an analytical laboratory, including a QC environment.
  • Practical HPLC experience with macromolecules is required. You should be confident operating the instrument independently, preparing samples, and following and applying written protocols.
  • Experience with capillary gel electrophoresis (CGE) and/or liquid chromatography–mass spectrometry (LC-MS) is an advantage.
  • Experience in analytical method development is desirable.
  • Fluency in Italian and English, with strong written and verbal communication skills in both languages.
  • Strong attention to detail, sound documentation habits and the ability to work independently and collaboratively.

Nice to have

  • Experience supporting mRNA, nucleic acid or other biomacromolecule development.
  • Familiarity with GLP or GMP environments.
  • Experience with additional analytical techniques such as DLS, ELISA and fluorometric method for nucleic acids quantification.
  • Experience preparing technical protocols, reports, SOPs or work instructions.

Interested in applying your analytical skills to mRNA development? We’d be glad to hear from you.

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